SNX18 antibody (AA 22-628)

Catalog No. ABIN7600697

This anti-SNX18 antibody is a Rabbit Polyclonal antibody detecting SNX18 in WB and ELISA. Suitable for Human and Rat.

Quick Overview for SNX18 antibody (AA 22-628) (ABIN7600697)

Target: SNX18 (Sorting Nexin 18 (SNX18))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SNX18 Antibody

Binding Specificity: AA 22-628

Purpose: Anti-SNX18 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SNX18 Antibody Picoband® (ABIN7600697). Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SNX18 recombinant protein (Position: R22-F628).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Ha°berg, K., Lundmark, R., & Carlsson, S. R. (2008). SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1-positive endosomal trafficking. Journal of cell science, 121(9), 1495-1505. 2. Okano, M., Matsuo, H., Nishimura, Y., Hozumi, K., Yoshioka, S., Tonoki, A., & Itoh, M. (2016). Mib1 modulates dynamin 2 recruitment via Snx18 to promote Dll1 endocytosis for efficient Notch signaling. Genes to Cells, 21(5), 425-441. 3. Willenborg, C., Jing, J., Wu, C., Matern, H., Schaack, J., Burden, J., & Prekeris, R. (2011). Interaction between FIP5 and SNX18 regulates epithelial lumen formation. Journal of Cell Biology, 195(1), 71-86.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SNX18

Target: SNX18 (Sorting Nexin 18 (SNX18))

Alternative Name: SNX18

Background:

Synonyms: Tudor domain-containing protein 3, TDRD3

Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Background: Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 69 kDa

Gene ID: 112574