Contactin 1 antibody (AA 225-979)

Catalog No. ABIN7600719

This Rabbit Polyclonal antibody specifically detects Contactin 1 in WB, ELISA, ICC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Contactin 1 antibody (AA 225-979) (ABIN7600719)

Target: Contactin 1 (CNTN1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Contactin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Contactin 1 Antibody

Binding Specificity: AA 225-979

Purpose: Anti-Contactin 1/CNTN1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Contactin 1/CNTN1 Antibody Picoband® (ABIN7600719). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Contactin 1/CNTN1 recombinant protein (Position: K225-H979).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Berglund, E. O., Murai, K. K., Fredette, B., Sekerkova, G., Marturano, B., Weber, L., Mugnaini, E., Ranscht, B. Ataxia and abnormal cerebellar microorganization in mice with ablated contactin gene expression. Neuron 24: 739-750, 1999. 2. Berglund, E. O., Ranscht, B. Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12. Genomics 21: 571-582, 1994. 3. Boyle, M. E. T., Berglund, E. O., Murai, K. K., Weber, L., Peles, E., Ranscht, B. Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve. Neuron 30: 385-397, 2001.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Contactin 1

Target: Contactin 1 (CNTN1)

Alternative Name: CNTN1

Background:

Synonyms: Ras-related protein Rab-11B, GTP-binding protein YPT3, RAB11B, YPT3

Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.

Background: Contactin 1, also known as CNTN1, is a protein which in humans is encoded by the CNTN1 gene. The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 135 kDa

Gene ID: 1272

UniProt: Q12860