CCL7 antibody (AA 24-97)

Catalog No. ABIN7600861

The Rabbit Polyclonal anti-CCL7 antibody has been validated for WB and ELISA. It is suitable to detect CCL7 in samples from Rat.

Quick Overview for CCL7 antibody (AA 24-97) (ABIN7600861)

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCL7 Antibody

Binding Specificity: AA 24-97

Purpose: Anti-Ccl7 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Ccl7 Antibody Picoband® (ABIN7600861). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived rat Ccl7 recombinant protein (Position: Q24-P97).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL, Rat
1. Ong, V. H., Evans, L. A., Shiwen, X., Fisher, I. B., Rajkumar, V., Abraham, D. J., Black, C. M., Denton, C. P.Monocyte chemoattractant protein 3 as a mediator of fibrosis: overexpression in systemic sclerosis and the type 1 tight-skin mouse.Arthritis Rheum. 48: 1979-1991, 2003. 2. McQuibban, G. A., Gong, J.-H., Tam, E. M., McCulloch, C. A. G., Clark-Lewis, I., Overall, C. M.Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.Science 289: 1202-1206, 2000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: Ccl7

Background:

Synonyms: Fatty acid-binding protein, intestinal,Fatty acid-binding protein 2,Intestinal-type fatty acid-binding protein,I-FABP,Fabp2,Fabpi,

Tissue Specificity: Expressed in the small intestine. Highest expression levels in the proximal ileum. .

Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

Molecular Weight: 9 kDa

Gene ID: 287561