ANG antibody (AA 25-145)

Catalog No. ABIN7600882

The Rabbit Polyclonal anti-ANG antibody has been validated for WB and ELISA. It is suitable to detect ANG in samples from Rat.

Quick Overview for ANG antibody (AA 25-145) (ABIN7600882)

Target: ANG (Angiogenin (ANG))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANG Antibody

Binding Specificity: AA 25-145

Purpose: Anti-Angiogenin/Ang Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Angiogenin/Ang Antibody Picoband® (ABIN7600882). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived rat Angiogenin/Ang recombinant protein (Position: Q25-L145).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL, Rat
1. Brown, W. E., Nobile, V., Subramanian, V., Shapiro, R. The mouse angiogenin gene family: structures of an angiogenin-related protein gene and two pseudogenes. Genomics 29: 200-206, 1995. 2. Crabtree, B., Thiyagarajan, N., Prior, S. H., Wilson, P., Iyer, S., Ferns, T., Shapiro, R., Brew, K., Subramanian, V., Acharya, K. R. Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis. Biochemistry 46: 11810-11818, 2007. 3. Gao, X., Hu, H., Zhu, J., Xu, Z. Identification and characterization of follistatin as a novel angiogenin-binding protein. FEBS Lett. 581: 5505-5510, 2007.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ANG

Target: ANG (Angiogenin (ANG))

Alternative Name: Ang

Background:

Synonyms: Angiogenin,3.1.27.-,Ribonuclease 5,RNase 5,ANG,RNASE5,

Tissue Specificity: Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons. .

Background: Angiogenin (ANG) also known as ribonuclease 5 is a small 123 amino acid protein that in humans is encoded by the ANG gene. Predicted to enable several functions, including actin binding activity, heparin binding activity, and protein homodimerization activity. Involved in liver development. Predicted to be located in several cellular components, including growth cone, neuronal cell body, and nucleolus. Predicted to be part of angiogenin-PRI complex. Human ortholog(s) of this gene implicated in diabetic retinopathy, myocardial infarction, neurodegenerative disease (multiple), and prostate cancer. Orthologous to human ANG (angiogenin).

Molecular Weight: 25 kDa

Gene ID: 305843