Fibrillin 2 antibody (AA 2740-2912)

Catalog No. ABIN7601047

The Rabbit Polyclonal anti-Fibrillin 2 antibody has been validated for ELISA and WB. It is suitable to detect Fibrillin 2 in samples from Human.

Quick Overview for Fibrillin 2 antibody (AA 2740-2912) (ABIN7601047)

Target: Fibrillin 2 (FBN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrillin 2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Fibrillin 2 Antibody

Binding Specificity: AA 2740-2912

Purpose: Anti-fibrillin 2/FBN2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-fibrillin 2/FBN2 Antibody Picoband® (ABIN7601047). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human fibrillin 2/FBN2 recombinant protein (Position: N2740-Y2912).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Babcock, D., Gasner, C., Francke, U., Maslen, C. A single mutation that results in an asp-to-his substitution and partial exon skipping in a family with congenital contractual arachnodactyly. Hum. Genet. 103: 22-28, 1998. 2. Belleh, S., Zhou, G., Wang, M., Der Kaloustian, V. M., Pagon, R. A., Godfrey, M. Two novel fibrillin-2 mutations in congenital contractural arachnodactyly. Am. J. Med. Genet. 92: 7-12, 2000. 3. Lee, B., Godfrey, M., Vitale, E., Hori, H., Mattei, M.-G., Sarfarazi, M., Tsipouras, P., Ramirez, F., Hollister, D. W. Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes. Nature 352: 330-334, 1991.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Fibrillin 2

Target: Fibrillin 2 (FBN2)

Alternative Name: FBN2

Background:

Synonyms: Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K (+) transport growth defect 1, Protein SKD1, VPS4B, SKD1, VPS42, MIG1

Tissue Specificity: Ubiquitously expressed.

Background: Fibrillin is a glycoprotein, which is essential for the formation of elastic fibers found in connective tissue. The protein encoded by this gene is a component of connective tissue microfibrils and may be involved in elastic fiber assembly. Mutations in this gene cause congenital contractural arachnodactyly.

Molecular Weight: 315 kDa, 250 kDa

Gene ID: 2201

UniProt: P35556

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome