RLBP1 antibody (AA 3-288)

Catalog No. ABIN7601185

The Rabbit Polyclonal anti-RLBP1 antibody has been validated for WB, ELISA and FACS. It is suitable to detect RLBP1 in samples from Human, Rat and Mouse.

Quick Overview for RLBP1 antibody (AA 3-288) (ABIN7601185)

Target: RLBP1 (Retinaldehyde Binding Protein 1 (RLBP1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RLBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RLBP1 Antibody

Binding Specificity: AA 3-288

Purpose: Anti-RLBP1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RLBP1 Antibody Picoband® (ABIN7601185). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RLBP1 recombinant protein (Position: E3-D288).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bear, J. C., Nemec, T. F., Kennedy, J. C., Marshall, W. H., Power, A. A., Kolonel, V. M., Burke, G. B. Inbreeding in outport Newfoundland. Am. J. Med. Genet. 29: 649-660, 1988. 2. Burstedt, M. S., Sandgren, O., Holmgren, G., Forsman-Semb, K. Bothnia dystrophy caused by mutations in the cellular retinaldehyde-binding protein gene (RLBP1) on chromosome 15q26. Invest. Ophthal. Vis. Sci. 40: 995-1000, 1999. 3. Burstedt, M. S. I., Forsman-Semb, K., Golovleva, I., Janunger, T., Wachtmeister, L., Sandgren, O. Ocular phenotype of Bothnia dystrophy, an autosomal recessive retinitis pigmentosa associated with an R234W mutation in the RLBP1 gene. Arch Ophthal. 119: 260-267, 2001.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RLBP1

Target: RLBP1 (Retinaldehyde Binding Protein 1 (RLBP1))

Alternative Name: RLBP1

Background:

Synonyms: POU domain, class 4, transcription factor 1

Tissue Specificity: Expressed in the brain and the retina. Present in the developing brain, spinal cord and eye.

Background: Retinaldehyde-binding protein 1 (RLBP1) also known as cellular retinaldehyde-binding protein (CRALBP) is a 36-kD water-soluble protein that in humans is encoded by the RLBP1 gene. The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens.

Molecular Weight: 36 kDa

Gene ID: 6017

UniProt: P12271