Fibulin 1 antibody (AA 30-703)

Catalog No. ABIN7601231

This anti-Fibulin 1 antibody is a Rabbit Polyclonal antibody detecting Fibulin 1 in WB, ICC, ELISA, FACS and IF. Suitable for Human.

Quick Overview for Fibulin 1 antibody (AA 30-703) (ABIN7601231)

Target: Fibulin 1 (FBLN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibulin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-Fibulin 1 Antibody

Binding Specificity: AA 30-703

Purpose: Anti-Fibulin 1/FBLN1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Fibulin 1/FBLN1 Antibody Picoband® (ABIN7601231). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Fibulin 1/FBLN1 recombinant protein (Position: D30-F703).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Argraves, W. S., Dickerson, K., Burgess, W. H., Ruoslahti, E. Fibulin, a novel protein that interacts with the fibronectin receptor-beta subunit cytoplasmic domain. Cell 58: 623-629, 1989. 2. Argraves, W. S., Tran, H., Burgess, W. H., Dickerson, K. Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure. J. Cell Biol. 111: 3155-3164, 1990. 3. Bohlega, S., Al-Ajlan, H., Al-Saif, A. Mutation of fibulin-1 causes a novel syndrome involving the central nervous system and connective tissues. Europ. J. Hum. Genet. 22: 640-643, 2014.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Fibulin 1

Target: Fibulin 1 (FBLN1)

Alternative Name: FBLN1

Background:

Synonyms: Insulin gene enhancer protein ISL-1,Islet-1,ISL1,

Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

Background: FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein. Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.

Molecular Weight: 90 kDa

Gene ID: 2192

UniProt: P23142