WDR24 antibody (AA 309-762)

Catalog No. ABIN7601246

Product Details anti-WDR24 Antibody

Target: WDR24 (WD Repeat Domain 24 (WDR24))

Binding Specificity: AA 309-762

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR24 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Anti-WDR24 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-WDR24 Antibody Picoband® (ABIN7601246). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WDR24 recombinant protein (Position: H309-H762).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Robert, A. , Saxton, Kevin, E. , Knockenhauer, Rachel, L. , & Wolfson, et al. (2016). Structural basis for leucine sensing by the sestrin2-mtorc1 pathway. Science (New York, N.Y.). 2. Wolfson, R. L. , Chantranupong, L. , Saxton, R. A. , Kuang, S. , Scaria, S. M. , & Cantor, J. R. , et al. (2016). [Research Article] Sestrin2 is a leucine sensor for the mTORC1 pathway. 3. Wang, D., Xu, C., Yang, W., Chen, J., Ou, Y., Guan, Y., ... & Liu, Y. (2022). E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression. Molecular Cell, 82(4), 770-784.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for WDR24

Target: WDR24 (WD Repeat Domain 24 (WDR24))

Alternative Name: WDR24 (WDR24 Products)

Background:

Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17

Background: WD repeat-containing protein 24 is a protein that in humans is encoded by the WDR24 gene. WDR24 is a component ofthe GATOR2 complex which hasfive known subunits(WDR24, WDR59, Mios, Sec13, and Seh1L). GATOR2 complex positively regulates mTORC1 signaling by acting upstream of orin parallel to GATOR1, which is a GTPase-activating protein (GAP) for RagA or RagB and an inhibitor ofthe amino-acid-sensing pathway.

Molecular Weight: 88 kDa

Gene ID: 84219

UniProt: Q96S15