HTRA4 antibody (AA 31-464)

Catalog No. ABIN7601271

This Rabbit Polyclonal antibody specifically detects HTRA4 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for HTRA4 antibody (AA 31-464) (ABIN7601271)

Target: HTRA4 (HtrA Serine Peptidase 4 (HTRA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTRA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-HTRA4 Antibody

Binding Specificity: AA 31-464

Purpose: Anti-HTRA4 Antibody Picoband®

Characteristics: Anti-HTRA4 Antibody Picoband® (ABIN7601271). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HTRA4 recombinant protein (Position: A31-D464). Human HTRA4 shares 68.7% and 68.9% amino acid (aa) sequence identity with mouse and rat HTRA4, respectively.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Clausen, T., Southan, C., Ehrmann, M. The HtrA family of proteases: implications for protein composition and cell fate. Molec. Cell 10: 443-455, 2002. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/12/2007.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for HTRA4

Target: HTRA4 (HtrA Serine Peptidase 4 (HTRA4))

Alternative Name: HTRA4

Background: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.

Molecular Weight: 51 kDa

Gene ID: 203100

UniProt: P83105