TNIP1 antibody (AA 312-371)

Catalog No. ABIN7601284

The Rabbit Polyclonal anti-TNIP1 antibody has been validated for WB and ELISA. It is suitable to detect TNIP1 in samples from Human, Mouse and Rat.

Quick Overview for TNIP1 antibody (AA 312-371) (ABIN7601284)

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TNIP1 Antibody

Binding Specificity: AA 312-371

Purpose: Anti-TNIP1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TNIP1 Antibody Picoband® (ABIN7601284). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TNIP1 recombinant protein (Position: E312-K371).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. El Bakkouri, K., Wullaert, A., Haegman, M., Heyninck, K., Beyaert, R. Adenoviral gene transfer of the NK-kappa-B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model. J. Biol. Chem. 280: 17938-17944, 2005. 2. Fukushi, M., Dixon, J., Kimura, T., Tsurutani, N., Dixon, M. J., Yamamoto, N. Identification and cloning of a novel cellular protein Naf1, Nef-associated factor 1, that increases cell surface CD4 expression. FEBS Lett. 442: 83-88, 1999. 3. Oshima, S., Turer, E. E., Callahan, J. A., Chai, S., Advincula, R., Barrera, J., Shifrin, N., Lee, B., Yen, B., Woo, T., Malynn, B. A., Ma, A. ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development. Nature 457: 906-909, 2009. Note: Erratum: Nature 458: 538 only, 2009.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for TNIP1

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Alternative Name: TNIP1

Background:

Synonyms: Tumor necrosis factor receptor superfamily member 14,Herpes virus entry mediator A,Herpesvirus entry mediator A,HveA,Tumor necrosis factor receptor-like 2,TR2,CD270,TNFRSF14,HVEA, HVEM,UNQ329/PRO509,

Tissue Specificity: Widely expressed, with the highest expression in lung, spleen and thymus.

Background: TNFAIP3-interacting protein 1 is a protein that in humans is encoded by the TNIP1 gene. This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 80-85 kDa

Gene ID: 10318

UniProt: Q15025

Pathways: Activation of Innate immune Response