STK3 antibody (AA 314-456)
Quick Overview for STK3 antibody (AA 314-456) (ABIN7601288)
Target
See all STK3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 314-456
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Purpose
- Anti-STK3/MST-2 Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-STK3/MST-2 Antibody (ABIN7601288). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human STK3/MST-2 recombinant protein (Position: E314-D456).
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Isotype
- IgG
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Application Notes
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Western blot, 0.1-0.25 μg/mL, Human, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- STK3 (serine/threonine Kinase 3 (STK3))
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Alternative Name
- STK3
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Background
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Synonyms: Cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta subunit, CD131, Csf2rb, Aic2b, Csf2rb1, Il3rb1
Tissue Specificity: Broadly expressed with higher expression in heart.
Background: Serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the STK3 gene. This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 56 kDa
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Gene ID
- 6788
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UniProt
- Q13188
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Pathways
- Tube Formation
Target
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