SFXN3 antibody (AA 32-321)

Catalog No. ABIN7601302

The Rabbit Polyclonal anti-SFXN3 antibody has been validated for WB, ELISA, IHC, IF and FACS. It is suitable to detect SFXN3 in samples from Human.

Quick Overview for SFXN3 antibody (AA 32-321) (ABIN7601302)

Target: SFXN3 (Sideroflexin 3 (SFXN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFXN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-SFXN3 Antibody

Binding Specificity: AA 32-321

Purpose: Anti-SFXN3 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SFXN3 Antibody Picoband® (ABIN7601302). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SFXN3 recombinant protein (Position: D32-L321).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fleming, M. D., Campagna, D. R., Haslett, J. N., Trenor, C. C., III, Andrews, N. C. A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. Genes Dev. 15: 652-657, 2001. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 12/17/2013. 3. Kory, N., Wyant, G. A., Prakash, G., iut de Bos, J., Bottanelli, F., Pacold, M. E., Chan, S. H., Lewis, C. A., Wang, T., Keys, H. R., Guo, Y. E., Sabatini, D. M. SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism. Science 362: eaat9528, 2018. Note: Electronic Article.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SFXN3

Target: SFXN3 (Sideroflexin 3 (SFXN3))

Alternative Name: SFXN3

Background:

Synonyms: DAP3-binding cell death enhancer 1, Death ligand signal enhancer, DELE1, DELE, KIAA0141

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: SFXN3, a mitochondrial membrane protein, is a member of sideroflexin family. Serum anti-SFXN3 autoantibody was elevated in early stage of the oral squamous cell carcinoma significantly, indicating its clinical value for diagnosis of oral squamous cell carcinoma.

Molecular Weight: 36 kDa

Gene ID: 81855

Pathways: Transition Metal Ion Homeostasis