ROM1 antibody (AA 32-337)

Catalog No. ABIN7601303

This anti-ROM1 antibody is a Rabbit Polyclonal antibody detecting ROM1 in WB, ELISA and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for ROM1 antibody (AA 32-337) (ABIN7601303)

Target: ROM1 (Retinal Outer Segment Membrane Protein 1 (ROM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-ROM1 Antibody

Binding Specificity: AA 32-337

Purpose: Anti-ROM1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-ROM1 Antibody Picoband® (ABIN7601303). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ROM1 recombinant protein (Position: G32-A337).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bascom, R. A., Connell, G., Garcia-Heras, J., Collins, L., Ledbetter, D., Molday, R. S., Kalnins, V., McInnes, R. R. Molecular and ultrastructural characterization of the products of the human retinopathy candidate genes ROM1 and RDS. (Abstract) Am. J. Hum. Genet. 47 (suppl.): A101 only, 1990. 2. Bascom, R. A., Garcia-Heras, J., Hsieh, C.-L., Gerhard, D. S., Jones, C., Francke, U., Willard, H. F., Ledbetter, D. H., McInnes, R. R. Localization of the photoreceptor gene ROM1 to human chromosome 11 and mouse chromosome 19: sublocalization to human 11q13 between PGA and PYGM. Am. J. Hum. Genet. 51: 1028-1035, 1992. 3. Bascom, R. A., Liu, L., Chen, J., Duncan, A., Kimberling, W. J., Moller, C. G., Humphries, P., Nathans, J., McInnes, R. R. ROM1: a candidate gene for autosomal dominant retinitis pigmentosa (ADRP), Usher syndrome type 1, and Best vitelliform macular dystrophy. (Abstract) Am. J. Hum. Genet. 51 (suppl.): A6 only, 1992.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ROM1

Target: ROM1 (Retinal Outer Segment Membrane Protein 1 (ROM1))

Alternative Name: ROM1

Background:

Synonyms: Forkhead box protein F1, Forkhead-related activator 1, FREAC-1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FOXF1, FKHL5, FREAC1

Tissue Specificity: Expressed in kidney.

Background: Rod outer segment membrane protein 1 is a protein that in humans is encoded by the ROM1 gene. This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.

Molecular Weight: 37 kDa

Gene ID: 6094

UniProt: Q03395