ST6GALNAC2 antibody (AA 32-374)

Catalog No. ABIN7601307

Product Details anti-ST6GALNAC2 Antibody

Target: ST6GALNAC2 (ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 2 (ST6GALNAC2))

Binding Specificity: AA 32-374

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST6GALNAC2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Anti-ST6GALNAC2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-ST6GALNAC2 Antibody Picoband® (ABIN7601307). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ST6GALNAC2 recombinant protein (Position: Q32-R374).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Samyn-Petit, B., Krzewinski-Recchi M.-A., Steelant, W. F. A., Delannoy, P., Harduin-Lepers, A. Molecular cloning and functional expression of human ST6GalNAc II: molecular expression in various human cultured cells. Biochim. Biophys. Acta 1474: 201-211, 2000. 2. Sotiropoulou, G., Kono, M., Anisowicz, A., Stenman, G., Tsuji, S., Sager, R. Identification and functional characterization of a human GalNAc alpha-2,6-sialyltransferase with altered expression in breast cancer. Molec. Med. 8: 42-55, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ST6GALNAC2

Target: ST6GALNAC2 (ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 2 (ST6GALNAC2))

Alternative Name: ST6GALNAC2 (ST6GALNAC2 Products)

Background:

Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA

Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Background: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 is an enzyme that in humans is encoded by the ST6GALNAC2 gene. ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting.

Molecular Weight: 40 kDa

Gene ID: 10610