QSOX1 antibody (AA 32-421)

Catalog No. ABIN7601310

This Rabbit Polyclonal antibody specifically detects QSOX1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for QSOX1 antibody (AA 32-421) (ABIN7601310)

Target: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QSOX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-QSOX1 Antibody

Binding Specificity: AA 32-421

Purpose: Anti-Quiescin Q6/QSOX1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Quiescin Q6/QSOX1 Antibody Picoband® (ABIN7601310). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Quiescin Q6/QSOX1 recombinant protein (Position: R32-Q421).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alon, A., Grossman, I., Gat, Y., Kodali, V. K., DiMaio, F., Mehlman, T., Haran, G., Baker, D., Thorpe, C., Fass, D. The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature 488: 414-418, 2012. 2. Coppock, D. L., Cina-Poppe, D., Gilleran, S. The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1. Genomics 54: 460-468, 1998. 3. Coppock, D. L., Kopman, C., Scandalis, S., Gilleran, S. Preferential gene expression in quiescent human lung fibroblasts. Cell Growth Differ. 4: 483-493, 1993.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for QSOX1

Target: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Alternative Name: QSOX1

Background:

Synonyms: Lymphotactin, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, Small-inducible cytokine C1, Xcl1, Lptn, Ltn, Scyc1

Tissue Specificity: Expressed in activated CD8 (+) T cells. In the thymus, expressed by medullary thymic epithelial cells.

Background: Sulfhydryl oxidase 1 is an enzyme that in humans is encoded by the QSOX1 gene. This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight: 105 kDa

Gene ID: 5768

UniProt: O00391

Pathways: Cell RedoxHomeostasis