PIGR antibody (AA 34-771)

Catalog No. ABIN7601403

This Rabbit Polyclonal antibody specifically detects PIGR in WB, ELISA and FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for PIGR antibody (AA 34-771) (ABIN7601403)

Target: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PIGR Antibody

Binding Specificity: AA 34-771

Purpose: Anti-Polymeric immunoglobulin receptor/PIGR Picoband® Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Polymeric immunoglobulin receptor/PIGR Picoband® Antibody (ABIN7601403). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Polymeric immunoglobulin receptor/PIGR recombinant protein (Position: D34-A771).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Davidson, M. K., Le Beau, M. M., Eddy, R. L., Shows, T. B., DiPietro, L. A., Kingzette, M., Hanly, W. C. Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31-q41. Cytogenet. Cell Genet. 48: 107-111, 1988. 2. Hood, L., Kronenberg, M., Hunkapiller, T. T cell antigen receptors and the immunoglobulin supergene family. Cell 40: 225-229, 1985. 3. Krajci, P., Gedde-Dahl, T., Jr., Hoyheim, B., Rogde, S., Olaisen, B., Brandtzaeg, P. The gene encoding human transmembrane secretory component (locus PIGR) is linked to D1S58 on chromosome 1. Hum. Genet. 90: 215-219, 1992.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for PIGR

Target: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Alternative Name: Pigr

Background:

Synonyms: Polymeric immunoglobulin receptor, PIgR, Poly-Ig receptor, Secretory component, Pigr

Tissue Specificity: Expressed in all tissues examined.

Background: Polymeric immunoglobulin receptor (pIgR) is a transmembrane protein that in humans is encoded by the PIGR gene. It is mapped to 1 E4, 1 56.89 cM. This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells, the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.

Molecular Weight: 85-100 kDa

Gene ID: 18703

UniProt: O70570