PIGR antibody (Polymeric Immunoglobulin Receptor) (AA 646-672)

Details for Product anti-PIGR Antibody No. ABIN652495, Supplier: Log in to see
Antigen
  • DKFZp469G1013
  • RNPIGR2
  • pIgA-R
  • polymeric immunoglobulin receptor
  • PIGR
  • Pigr
Epitope
AA 646-672, C-Term
19
8
7
6
6
5
5
5
5
5
5
5
4
4
3
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
71
28
23
16
3
2
2
1
1
Host
Rabbit
126
5
2
Clonality (Clone)
Polyclonal ()
Conjugate
This PIGR antibody is un-conjugated
19
16
6
2
2
2
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
103
78
46
21
18
12
11
11
5
2
2
1
1
1
1
Options
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Immunogen This PIGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-672 AA from the C-terminal region of human PIGR.
Clone RB22328
Isotype Ig Fraction
Specificity This PIGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652~681 amino acids from the C-terminal region of human PIGR.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name PIGR (PIGR Antibody Abstract)
Background PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Synonyms: Polymeric immunoglobulin receptor, Poly-Ig receptor, PIGR, Hepatocellular carcinoma-associated protein TB6, Secretory component, PIGR
Pathways: Intestinal immune network for IgA production
Molecular Weight 83284 Da
Gene ID 5284
UniProt P01833
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Polymeric Immunoglobulin Receptor (PIGR) (AA 646-672), (C-Term) antibody (ABIN652495) Western blot analysis of PIGR Antibody (C-term) (ABIN652495) in HepG2,K562,HL-60 cell...
Immunohistochemistry (IHC) image for anti-Polymeric Immunoglobulin Receptor (PIGR) (AA 646-672), (C-Term) antibody (ABIN652495) Formalin-fixed and paraffin-embedded human hepatocarcinoma with PIGR Antibody (C-term...
Flow Cytometry (FACS) image for anti-Polymeric Immunoglobulin Receptor (PIGR) (AA 646-672), (C-Term) antibody (ABIN652495) Flow cytometric analysis of HepG2 cells using PIGR Antibody (C-term)(bottom histogram...
Background publications Orzech, Cohen, Weiss, Aroeti: "Interactions between the exocytic and endocytic pathways in polarized Madin-Darby canine kidney cells." in: The Journal of biological chemistry, Vol. 275, Issue 20, pp. 15207-19, 2000 (PubMed).

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