RETSAT antibody (AA 35-597)

Catalog No. ABIN7601433

Product Details anti-RETSAT Antibody

Target: RETSAT (Retinol Saturase (All-Trans-Retinol 13,14-Reductase) (RETSAT))

Binding Specificity: AA 35-597

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RETSAT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: Anti-RETSAT Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RETSAT Antibody Picoband® (ABIN7601433). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RETSAT recombinant protein (Position: E35-K597).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 7/26/2017. 2. Moise, A. R., Kuksa, V., Imanishi, Y., Palczewski, K. Identification of all-trans-retinol:all-trans-13,14-dihydroretinol saturase. J. Biol. Chem. 279: 50230-50242, 2004. 3. Schupp, M., Lefterova, M. I., Janke, J., Leitner, K., Cristancho, A. G., Mullican, S. E., Qatanani, M., Szwergold, N., Steger, D. J., Curtin, J. C., Kim, R. J., Suh, M.-J., Albert, M. R., Engeli, S., Gudas, L. J., Lazar, M. A. Retinol saturase promotes adipogenesis and is downregulated in obesity. Proc. Nat. Acad. Sci. 106: 1105-1110, 2009. Note: Erratum: Proc. Nat. Acad. Sci. 106: 4571 only, 2009.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RETSAT

Target: RETSAT (Retinol Saturase (All-Trans-Retinol 13,14-Reductase) (RETSAT))

Alternative Name: RETSAT (RETSAT Products)

Background:

Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7

Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Background: In enzymology, an all-trans-retinol 13,14-reductase is an enzyme, encoded by the RETSAT gene. Predicted to enable all-trans-retinol 13,14-reductase activity. Predicted to be involved in retinol metabolic process. Located in membrane.

Molecular Weight: 67 kDa

Gene ID: 54884