OAS2 antibody (AA 35-742)

Catalog No. ABIN7601436

This Rabbit Polyclonal antibody specifically detects OAS2 in WB, ELISA and FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for OAS2 antibody (AA 35-742) (ABIN7601436)

Target: OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-OAS2 Antibody

Binding Specificity: AA 35-742

Purpose: Anti-OAS2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-OAS2 Antibody (ABIN7601436). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse OAS2 recombinant protein (Position: H35-K742). Mouse OAS2 shares 62.4% and 77.5% amino acid (aa) sequence identity with human and rat ATF5, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
ELISA, 0.1-0.5 μg/mL, Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for OAS2

Target: OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

Alternative Name: OAS2

Background:

Synonyms: Oas2, oasl11, 2'-5'-oligoadenylate synthase 2, (2-5'oligo(A synthase 2, 2-5A synthase 2, EC 2.7.7.84, 2',5'-oligoadenylate synthetase-like 11

Background: 2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene. Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Involved in defense response to virus, regulation of lactation, and type I interferon signaling pathway. Acts upstream of or within RNA catabolic process, interleukin-27-mediated signaling pathway, and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol, membrane, and nucleoplasm. Is expressed in embryo. Orthologous to human OAS2 (2'-5'-oligoadenylate synthetase 2).

Molecular Weight: 69 kDa

Gene ID: 246728

UniProt: E9Q9A9

Pathways: Hepatitis C