MPZL1 antibody (AA 37-269)

Catalog No. ABIN7601496

Product Details anti-MPZL1 Antibody

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Binding Specificity: AA 37-269

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-MPZL1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MPZL1 Antibody Picoband® (ABIN7601496). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MPZL1 recombinant protein (Position: A37-N269).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Paardekooper Overman, J., Yi, J.-S., Bonetti, M., Soulsby, M., Preisinger, C., Stokes, M. P., Hui, L., Silva, J. C., Overvoorde, J., Giansanti, P., Heck, A. J. R., Kontaridis, M. I., den Hertog, J., Bennett, A. M. PZR coordinates Shp2 Noonan and LEOPARD syndrome signaling in zebrafish and mice. Molec. Cell. Biol. 34: 2874-2889, 2014. 2. Zannettino, A. C. W., Roubelakis, M., Welldon, K. J., Jackson, D. E., Simmons, P. J., Bendall, L. J., Henniker, A., Harrison, K. L., Niutta, S., Bradstock, K. F., Watt, S. M. Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration. Biochem. J. 370: 537-549, 2003.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MPZL1

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Alternative Name: MPZL1 (MPZL1 Products)

Background:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, USP21, USP23, PP1490

Tissue Specificity: Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.

Background: Myelin protein zero-like protein 1 is a protein that in humans is encoded by the MPZL1 gene. MPZL1 is a cell surface receptor, which is involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. MPZL1 is a major receptor for concanavalin A (ConA) and is involved in cell.

Molecular Weight: 29-37 kDa

Gene ID: 9019

UniProt: O95297