SOCS5 antibody (AA 386-536)

Catalog No. ABIN7601562

This Rabbit Polyclonal antibody specifically detects SOCS5 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for SOCS5 antibody (AA 386-536) (ABIN7601562)

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SOCS5 Antibody

Binding Specificity: AA 386-536

Purpose: Anti-SOCS5 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SOCS5 Antibody (ABIN7601562). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SOCS5 recombinant protein (Position: M386-K536).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for SOCS5

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Alternative Name: SOCS5

Background:

Synonyms: Suppressor of cytokine signaling 5, SOCS-5, Cytokine-inducible SH2 protein 6, CIS-6, Cytokine-inducible SH2-containing protein 5, SOCS5, CIS6, CISH5, CISH6, KIAA0671

Tissue Specificity: Widely expressed. Expressed in TH1 but not TH2 cells.

Background: Suppressor of cytokine signaling 5 is a protein that in humans is encoded by the SOCS5 gene. It is mapped to 2p21. The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Molecular Weight: 61 kDa

Gene ID: 9655

UniProt: O75159

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process