CDK16 antibody (AA 392-443)

Catalog No. ABIN7601590

The Rabbit Polyclonal anti-CDK16 antibody has been validated for WB, ELISA, IHC and FACS. It is suitable to detect CDK16 in samples from Human, Mouse and Rat.

Quick Overview for CDK16 antibody (AA 392-443) (ABIN7601590)

Target: CDK16 (Cyclin-Dependent Kinase 16 (CDK16))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CDK16 Antibody

Binding Specificity: AA 392-443

Purpose: Anti-PCTAIRE1/CDK16 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PCTAIRE1/CDK16 Antibody Picoband® (ABIN7601590). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCTAIRE1/CDK16 recombinant protein (Position: N392-H443).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Knight, J. C., Renwick, P. J., Downing, J. R., Okuda, T. Physical linkage of the cdc2-related gene (PCTK1) and the ubiquitin-activating enzyme E1 gene (UBE1) on human Xp11.3. Cytogenet. Cell Genet. 71: 155-157, 1995. 2. Meyerson, M., Enders, G. H., Wu, C.-L., Su, L.-K., Gorka, C., Nelson, C., Harlow, E., Tsai, L.-H. A family of human cdc2-related protein kinases. EMBO J. 11: 2909-2917, 1992. 3. Okuda, T., Cleveland, J. L., Downing, J. R. PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene 7: 2249-2258, 1992.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CDK16

Target: CDK16 (Cyclin-Dependent Kinase 16 (CDK16))

Alternative Name: CDK16

Background:

Synonyms: Cyclin-dependent kinase 16 (EC:2.7.11.22), Cell division protein kinase 16, PCTAIRE-motif protein kinase 1, Serine/threonine-protein kinase PCTAIRE-1, CDK16, PCTAIRE1, PCTK1

Tissue Specificity: Detected in pancreas islets (at protein level). Detected in brain and pancreas.

Background: Cyclin-dependent kinase 16 is a protein that in humans is encoded by the CDK16 gene. This gene is mapped to Xp11.3. The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells, in exocytosis, and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 56 kDa

Gene ID: 5127

UniProt: Q00536

Pathways: Hormone Transport