NVL antibody (AA 4-807)

Catalog No. ABIN7601633

This anti-NVL antibody is a Rabbit Polyclonal antibody detecting NVL in WB, ELISA, IHC, IF, FACS and ICC. Suitable for Human and Rat.

Quick Overview for NVL antibody (AA 4-807) (ABIN7601633)

Target: NVL (Nuclear VCP-Like (NVL))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NVL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-NVL Antibody

Binding Specificity: AA 4-807

Purpose: Anti-NVL Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-NVL Antibody Picoband® (ABIN7601633). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NVL recombinant protein (Position: R4-Q807).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Germain-Lee, E. L., Obie, C., Valle, D. NVL: a new member of the AAA family of ATPases localized to the nucleus. Genomics 44: 22-34, 1997.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for NVL

Target: NVL (Nuclear VCP-Like (NVL))

Alternative Name: NVL

Background:

Synonyms: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4

Tissue Specificity: Ubiquitous.

Background: Nuclear valosin-containing protein-like is a protein that in humans is encoded by the NVL gene. This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.

Molecular Weight: 95 kDa

Gene ID: 4931

UniProt: O15381