GAS1 antibody (AA 40-288)

Catalog No. ABIN7601642

This anti-GAS1 antibody is a Rabbit Polyclonal antibody detecting GAS1 in WB, ELISA and FACS. Suitable for Human.

Quick Overview for GAS1 antibody (AA 40-288) (ABIN7601642)

Target: GAS1 (Growth Arrest-Specific 1 (GAS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-GAS1 Antibody

Binding Specificity: AA 40-288

Purpose: Anti-GAS1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-GAS1 Antibody Picoband® (ABIN7601642). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GAS1 recombinant protein (Position: L40-D288).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Allen, B. L., Tenzen, T., McMahon, A. P. The hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development. Genes Dev. 21: 1244-1257, 2007. 2. Colombo, M. P., Martinotti, A., Howard, T. A., Schneider, C., D'Eustachio, P., Seldin, M. F. Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16. Mammalian Genome 2: 130-134, 1992. 3. Del Sal, G., Collavin, L., Ruaro, M. E., Edomi, P., Saccone, S., Della Valle, G., Schneider, C. Structure, function, and chromosome mapping of the growth-suppressing human homologue of the murine gas1 gene. Proc. Nat. Acad. Sci. 91: 1848-1852, 1994.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for GAS1

Target: GAS1 (Growth Arrest-Specific 1 (GAS1))

Alternative Name: GAS1

Background:

Synonyms: Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10, TPR repeat protein 10, IFT88, TG737, TTC10

Tissue Specificity: Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.

Background: Growth arrest-specific protein 1 is a protein that in humans is encoded by the GAS1 gene. Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.

Molecular Weight: 40 kDa

Gene ID: 2619

UniProt: P54826