TTC29 antibody (AA 40-460)

Catalog No. ABIN7601649

Product Details anti-TTC29 Antibody

Target: TTC29 (Tetratricopeptide Repeat Domain 29 (TTC29))

Binding Specificity: AA 40-460

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: ELISA, Flow Cytometry (FACS), Western Blotting (WB)

Purpose: Anti-TTC29 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TTC29 Antibody Picoband® (ABIN7601649). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TTC29 recombinant protein (Position: D40-R460).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 1/10/2019. 2. Liu, C., He, X., Liu, W., Yang, S., Wang, L., Li, W., Wu, H., Tang, S., Ni, X., Wang, J., Gao, Y., Tian, S., and 12 others. Bi-allelic mutations in TTC29 cause male subfertility with asthenoteratospermia in humans and mice. Am. J. Hum. Genet. 105: 1168-1181, 2019. 3. Lores, P., Dacheux, D., Kherraf, Z.-E., Nsota Mbango, J.-F., Coutton, C., Stouvenel, L., Ialy-Radio, C., Amiri-Yekta, A., Whitfield, M., Schmitt, A., Cazin, C., Givelet, M., and 24 others. Mutations in TTC29, encoding an evolutionarily conserved axonemal protein, result in asthenozoospermia and male infertility. Am. J. Hum. Genet. 105: 1148-1167, 2019.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TTC29

Target: TTC29 (Tetratricopeptide Repeat Domain 29 (TTC29))

Alternative Name: TTC29 (TTC29 Products)

Background:

Synonyms: Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1, PYROXD1

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: Involved in cilium movement and cilium organization. Located in sperm flagellum. Implicated in spermatogenic failure 42.

Molecular Weight: 55 kDa

Gene ID: 83894