SEC24A antibody (AA 43-1045)

Catalog No. ABIN7601709

Product Details anti-SEC24A Antibody

Target: SEC24A (SEC24 Family, Member A (SEC24A))

Binding Specificity: AA 43-1045

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC24A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: Anti-SEC24A Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SEC24A Antibody Picoband® (ABIN7601709). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SEC24A recombinant protein (Position: Q43-Q1045).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Monkey
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Pagano, A., Letourneur, F., Garcia-Estefania, D., Carpentier, J.-L., Orci, L., Paccaud, J.-P. Sec24 proteins and sorting at the endoplasmic reticulum. J. Biol. Chem. 274: 7833-7844, 1999. 2. Tang, B. L., Kausalya, J., Low, D. Y. H., Lock, M. L., Hong, W. A family of mammalian proteins homologous to yeast Sec24p. Biochem. Biophys. Res. Commun. 258: 679-684, 1999.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SEC24A

Target: SEC24A (SEC24 Family, Member A (SEC24A))

Alternative Name: SEC24A (SEC24A Products)

Background:

Synonyms: Cationic amino acid transporter 3,CAT-3,CAT3,Cationic amino acid transporter y+,Solute carrier family 7 member 3,SLC7A3,ATRC3, CAT3,

Tissue Specificity: Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. .

Background: SEC24 family, member A (S. cerevisiae) is a protein that in humans is encoded by the SEC24A gene. The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 120 kDa

Gene ID: 10802

UniProt: O95486