RMDN3 antibody (AA 45-438)

Catalog No. ABIN7601775

This Rabbit Polyclonal antibody specifically detects RMDN3 in WB, ELISA, IHC, IF, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for RMDN3 antibody (AA 45-438) (ABIN7601775)

Target: RMDN3 (FAM82A2) (Family with Sequence Similarity 82, Member A2 (FAM82A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RMDN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-RMDN3 Antibody

Binding Specificity: AA 45-438

Purpose: Anti-PTPIP51/RMDN3 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PTPIP51/RMDN3 Antibody Picoband® (ABIN7601775). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PTPIP51/RMDN3 recombinant protein (Position: Q45-R438).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. De Vos, K. J., Morotz, G. M., Stoica, R., Tudor, E. L., Lau, K.-F., Ackerly, S., Warley, A., Shaw, C. E., Miller, C. C. J. VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis. Hum. Molec. Genet. 21: 1299-1311, 2012. 2. Lv, B. F., Yu, C. F., Chen, Y. Y., Lu, Y., Guo, J. H., Song, Q. S., Ma, D. L., Shi, T. P., Wang, L. Protein tyrosine phosphatase interacting protein 51 (PTPIP51) is a novel mitochondria protein with an N-terminal mitochondrial targeting sequence and induces apoptosis. Apoptosis 11: 1489-1501, 2006. 3. Oishi, K., Okano, H., Sawa H. RMD-1, a novel microtubule-associated protein, functions in chromosome segregation in Caenorhabditis elegans. J. Cell Biol. 179: 1149-1162, 2007. Note: Erratum: J. Cell Biol. 186: 629 only, 2009.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RMDN3

Target: RMDN3 (FAM82A2) (Family with Sequence Similarity 82, Member A2 (FAM82A2))

Alternative Name: RMDN3

Background:

Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: Regulator of microtubule dynamics protein 3 (RMDN3), more commonly known as Protein tyrosine phosphatase interacting protein 51 (PTPIP51), is a protein that in humans is encoded by the RMDN3 gene on chromosome 15. Enables microtubule binding activity. Involved in cellular calcium ion homeostasis. Located in several cellular components, including intercellular bridge, mitochondrial outer membrane, and spindle.

Molecular Weight: 55 kDa

Gene ID: 55177