HMMR antibody (AA 5-686)
Quick Overview for HMMR antibody (AA 5-686) (ABIN7601892)
Target
See all HMMR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 5-686
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Purpose
- Anti-CD168/HMMR Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-/HMMR Antibody (ABIN7601892). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human CD168/HMMR recombinant protein (Position: K5-D686).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))
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Alternative Name
- HMMR
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Background
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Synonyms: Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168, HMMR, IHABP, RHAMM
Tissue Specificity: May be up-regulated in bone metastatic breast cancer cells.
Background: Hyaluronan-mediated motility receptor (HMMR), also known as RHAMM (Receptor for Hyaluronan Mediated Motility) is a protein which in humans is encoded by the HMMR gene. It is mapped to 5q34. The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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Molecular Weight
- 84 kDa
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Gene ID
- 3161
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UniProt
- O75330
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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