SNX5 antibody (AA 50-404)

Catalog No. ABIN7601910

This Rabbit Polyclonal antibody specifically detects SNX5 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for SNX5 antibody (AA 50-404) (ABIN7601910)

Target: SNX5 (Sorting Nexin 5 (SNX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-SNX5 Antibody

Binding Specificity: AA 50-404

Purpose: Anti-SNX5 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SNX5 Antibody Picoband® (ABIN7601910). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SNX5 recombinant protein (Position: H50-N404).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, D., Xiao, H., Zhang, K., Wang, B., Gao, Z., Jian, Y., Qi, X., Sun, J., Miao, L., Yang, C. Retromer is required for apoptotic cell clearance by phagocytic receptor recycling. Science 327: 1261-1264, 2010. 2. Otsuki, T., Kajigaya, S., Ozawa, K., Liu, J. M. SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein. Biochem. Biophys. Res. Commun. 265: 630-635, 1999.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SNX5

Target: SNX5 (Sorting Nexin 5 (SNX5))

Alternative Name: SNX5

Background:

Synonyms: Ras GTPase-activating-like protein IQGAP2, IQGAP2

Tissue Specificity: Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine.

Background: Sorting nexin-5 is a protein that in humans is encoded by the SNX5 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 47 kDa

Gene ID: 27131

UniProt: Q9Y5X3