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HSPA4L antibody (AA 55-788)

The Rabbit Polyclonal anti-HSPA4L antibody has been validated for WB, ELISA, FACS, IF and ICC. It is suitable to detect HSPA4L in samples from Human, Mouse and Rat.
Catalog No. ABIN7602025

Quick Overview for HSPA4L antibody (AA 55-788) (ABIN7602025)

Target

See all HSPA4L Antibodies
HSPA4L (Heat Shock 70kDa Protein 4-Like (HSPA4L))

Reactivity

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Human, Mouse, Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This HSPA4L antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Binding Specificity

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    AA 55-788

    Purpose

    Anti-HSPA4L Antibody Picoband®

    Cross-Reactivity (Details)

    No cross reactivity with other proteins.

    Characteristics

    Anti-HSPA4L Antibody Picoband® (ABIN7602025). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human HSPA4L recombinant protein (Position: Q55-K788). Human HSPA4L shares 93.1% amino acid (aa) sequence identity with mouse HSPA4L.

    Isotype

    IgG
  • Application Notes

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Held, T., Paprotta, I., Khulan, J., Hemmerlein, B., Binder, L., Wolf, S., Schubert, S., Meinhardt, A., Engel, W., Adham, I. M. Hspa4l-deficient mice display increased incidence of male infertility and hydronephrosis development. Molec. Cell. Biol. 26: 8099-8108, 2006. 2. Liu, X., Wang, X., Liu, F. Decreased expression of heat shock protein A4L in spermatozoa is positively related to poor human sperm quality. Molec. Reprod. Dev. 86: 379-386, 2019. 3. Mohamed, B. A., Barakat, A. Z., Held, T., Elkenani, M., Muhlfeld, C., Manner, J., Adham, I. M. Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice. Am. J. Resp. Cell Molec. Biol. 50: 817-824, 2014.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    HSPA4L (Heat Shock 70kDa Protein 4-Like (HSPA4L))

    Alternative Name

    HSPA4L

    Background

    Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

    Tissue Specificity: Expressed in all tissues.

    Background: Heat shock 70 kDa protein 4L is a protein that in humans is encoded by the HSPA4L gene. The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene.

    Molecular Weight

    95 kDa

    Gene ID

    22824

    UniProt

    O95757
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