RANBP1 antibody (AA 57-194)

Catalog No. ABIN7602058

The Rabbit Polyclonal anti-RANBP1 antibody is suitable to detect RANBP1 in samples from Human. It has been validated for WB, ELISA, IF and ICC.

Quick Overview for RANBP1 antibody (AA 57-194) (ABIN7602058)

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-RANBP1 Antibody

Binding Specificity: AA 57-194

Purpose: Anti-RANBP1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RANBP1 Antibody (ABIN7602058). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RANBP1 recombinant protein (Position: R57-K194).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RANBP1

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Alternative Name: RANBP1

Background:

Synonyms: Ran-specific GTPase-activating protein,Ran-binding protein 1,RanBP1,RANBP1,

Tissue Specificity: Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. In the kidney, it is widely expressed in tubules, but sparsely expressed in the glomerulus (PubMed:24676636). Expression is significantly increased in renal biopsy specimens from idiopathic FSGS (PubMed:24676636). Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors.

Background: Ran-specific binding protein 1 is an enzyme that in humans is encoded by the RANBP1 gene. This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants.

Molecular Weight: 25 kDa

Gene ID: 5902

UniProt: P43487