OSBPL2 antibody (AA 6-480)

Catalog No. ABIN7602137

Product Details anti-OSBPL2 Antibody

Target: OSBPL2 (Oxysterol Binding Protein-Like 2 (OSBPL2))

Binding Specificity: AA 6-480

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSBPL2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Purpose: Anti-OSBPL2 Antibody Picoband®

Characteristics: Anti-OSBPL2 Antibody Picoband® (ABIN7602137). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human OSBPL2 recombinant protein (Position: E6-Y480). Human OSBPL2 shares 89% amino acid (aa) sequence identity with mouse OSBPL2.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Jaworski, C. J., Moreira, E., Li, A., Lee, R., Rodriguez, I. R. A family of 12 human genes containing oxysterol-binding domains. Genomics 78: 185-196, 2001. 2. Laitinen, S., Olkkonen, V. M., Ehnholm, C., Ikonen, E. Family of human oxysterol binding protein (OSBP) homologues: a novel member implicated in brain sterol metabolism. J. Lipid Res. 40: 2204-2211, 1999. 3. Lehto, M., Laitinen, S., Chinetti, G., Johansson, M., Ehnholm, C., Staels, B., Ikonen, E., Olkkonen, V. M. The OSBP-related protein family in humans. J. Lipid Res. 42: 1203-1213, 2001.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for OSBPL2

Target: OSBPL2 (Oxysterol Binding Protein-Like 2 (OSBPL2))

Alternative Name: OSBPL2 (OSBPL2 Products)

Background: Oxysterol-binding protein-related protein 2 is a protein that in humans is encoded by the OSBPL2 gene. This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Molecular Weight: 55 kDa

Gene ID: 9885

UniProt: Q9H1P3