PLA2G4B antibody (AA 61-781)

Catalog No. ABIN7602174

This Rabbit Polyclonal antibody specifically detects PLA2G4B in WB, ELISA and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PLA2G4B antibody (AA 61-781) (ABIN7602174)

Target: PLA2G4B (Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G4B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PLA2G4B Antibody

Binding Specificity: AA 61-781

Purpose: Anti-cPLA2 beta/PLA2G4B Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-cPLA2 beta/PLA2G4B Antibody Picoband® (ABIN7602174). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human cPLA2 beta/PLA2G4B recombinant protein (Position: N61-H781).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Pickard, R. T., Strifler, B. A., Kramer, R. M., Sharp, J. D. Molecular cloning of two new human paralogs of 85- kDa cytosolic phospholipase A2. J. Biol. Chem. 274: 8823-8831, 1999.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for PLA2G4B

Target: PLA2G4B (Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B))

Alternative Name: PLA2G4B

Background:

Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7

Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Background: Phospholipase A2, group IVB (cytosolic), also known as PLA2G4B, is a human gene. This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through transcripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic phospholipase A2 domains.

Molecular Weight: 88 kDa

Gene ID: 100137049

UniProt: P0C869

Pathways: ER-Nucleus Signaling, VEGF Signaling