BPIFA1 antibody (AA 64-256)

Catalog No. ABIN7602215

Product Details anti-BPIFA1 Antibody

Target: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Binding Specificity: AA 64-256

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPIFA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-Plunc/BPIFA1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Plunc/BPIFA1 Antibody Picoband® (ABIN7602215). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Plunc/BPIFA1 recombinant protein (Position: L64-V256).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Bingle, C. D., Bingle, L. Characterisation of the human plunc gene, a gene product with an upper airways and nasopharyngeal restricted expression pattern. Biochim. Biophys. Acta 1493: 363-367, 2000. 2. Bingle, C. D., Craven, C. J. PLUNC: A novel family of candidate host defence proteins expressed in the upper airways and nasopharynx. Hum. Molec. Genet. 11: 937-943, 2002. 3. Chu, H. W., Thaikoottathil, J., Rino, J. G., Zhang, G., Wu, Q., Moss, T., Refaeli, Y., Bowler, R., Wenzel, S. E., Chen, Z., Zdunek, J., Breed, R., Young, R., Allaire, E., Martin, R. J. Function and regulation of SPLUNC1 protein in mycoplasma infection and allergic inflammation. J. Immun. 179: 3995-4002, 2007.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for BPIFA1

Target: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Alternative Name: BPIFA1 (BPIFA1 Products)

Background:

Synonyms: IFNGR2 protein, Interferon gamma receptor 2, IFNGR2, mCG_11456

Tissue Specificity: Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

Background: Palate, lung, and nasal epithelium clone protein[5] (PLUNC) is a gene encoding a secretory protein. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.

Molecular Weight: 27 kDa

Gene ID: 51297