BPIFA1 antibody (Middle Region)

Catalog No. ABIN2775437

The Rabbit Polyclonal anti-BPIFA1 antibody (ABIN2775437) specifically detects BPIFA1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Goat and Rabbit samples.

Quick Overview for BPIFA1 antibody (Middle Region) (ABIN2775437)

Target: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Goat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPIFA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BPIFA1 Antibody

Binding Specificity: Middle Region

Purpose: PLUNC Antibody - middle region

Sequence: GLNNIIDIKV TDPQLLELGL VQSPDGHRLY VTIPLGIKLQ VNTPLVGASL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PLUNC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLUNC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42475-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BPIFA1

Target: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Alternative Name: PLUNC

Background:

Background Information: PLUNC is the human homolog of murine plunc and is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this protein is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer.This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only two is known.

Gene Name: BPI fold containing family A, member 1

Alternative Symbols: LUNX, NASG, PLUNC, SPURT, SPLUNC1, bA49G10.5

Protein Name: BPI fold-containing family A member 1

Molecular Weight: 28kDa

Gene ID: 51297

NCBI Accession: NP_057667

UniProt: Q9NP55