SERINC5 antibody (AA 64-394)

Catalog No. ABIN7602218

Product Details anti-SERINC5 Antibody

Target: SERINC5 (Serine Incorporator 5 (SERINC5))

Binding Specificity: AA 64-394

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERINC5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Anti-SERINC5 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SERINC5 Antibody Picoband® (ABIN7602218). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SERINC5 recombinant protein (Position: E64-H394).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 3/23/2012. 2. Inuzuka, M., Hayakawa, M., Ingi, T. Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis. J. Biol. Chem. 280: 35776-35783, 2005. 3. Rosa, A., Chande, A., Ziglio, S., De Sanctis, V., Bertorelli, R., Goh, S. L., McCauley, S. M., Nowosielska, A., Antonarakis, S. E., Luban, J., Santoni, F. A., Pizzato, M. HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation. Nature 526: 212-217, 2015.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SERINC5

Target: SERINC5 (Serine Incorporator 5 (SERINC5))

Alternative Name: SERINC5 (SERINC5 Products)

Background:

Synonyms: Inorganic pyrophosphatase 2, mitochondrial, Pyrophosphatase SID6-306, Pyrophosphate phospho-hydrolase 2, PPase 2, PPA2, HSPC124

Tissue Specificity: Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.

Background: Serine incorporator 5 is a protein that in humans is encoded by the SERINC5 gene. Predicted to enable L-serine transmembrane transporter activity. Involved in defense response to virus, detection of virus, and innate immune response. Located in several cellular components, including centrosome, cytosol, and plasma membrane

Molecular Weight: 65 kDa

Gene ID: 256987