REM2 antibody (AA 65-257)

Catalog No. ABIN7602227

Product Details anti-REM2 Antibody

Target: REM2 (RAS (RAD and GEM)-Like GTP Binding 2 (REM2))

Binding Specificity: AA 65-257

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: Anti-REM2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-REM2 Antibody Picoband® (ABIN7602227). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human REM2 recombinant protein (Position: R65-E257). Human REM2 shares 94.8% and 95.9% amino acid (aa) sequence identity with mouse and rat REM2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Bierings, R., Beato, M., Edel, M. J. An endothelial cell genetic screen identifies the GTPase Rem2 as a suppressor of p19(ARF) expression that promotes endothelial cell proliferation and angiogenesis. J. Biol. Chem. 283: 4408-4416, 2008. 2. Edel, M. J., Menchon, C., Menendez, S., Consiglio, A., Raya, A., Belmonte, J. C. I. Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. Genes Dev. 24: 561-573, 2010. 3. Finlin, B. S., Shao, H., Kadono-Okuda, K., Guo, N., Andres, D. A. Rem2, a new member of the Rem/Rad/Gem/Kir family of Ras-related GTPases. Biochem. J. 347: 223-231, 2000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for REM2

Target: REM2 (RAS (RAD and GEM)-Like GTP Binding 2 (REM2))

Alternative Name: REM2 (REM2 Products)

Background:

Synonyms: REM2, GTP-binding protein REM 2, Rad and Gem-like GTP-binding protein 2

Background: Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be involved in negative regulation of high voltage-gated calcium channel activity. Predicted to be active in plasma membrane.

Molecular Weight: 37 kDa

Gene ID: 161253