Seryl-tRNA Synthetase (SARS) (AA 71-483) antibody

Catalog No. ABIN7602365

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB, ELISA, IF, FACS and ICC. Suitable for Human, Mouse and Rat.

Quick Overview for Seryl-tRNA Synthetase (SARS) (AA 71-483) antibody (ABIN7602365)

Target: Seryl-tRNA Synthetase (SARS)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details

Binding Specificity: AA 71-483

Purpose: Anti-Seryl-tRNA synthetase/SERS/SARS1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Seryl-tRNA synthetase/SERS/SARS1 Antibody Picoband® (ABIN7602365). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Seryl-tRNA synthetase/SERS/SARS1 recombinant protein (Position: K71-K483).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fukui, H., Hanaoka, R., Kawahara, A. Noncanonical activity of seryl-tRNA synthetase is involved in vascular development. Circ. Res. 104: 1253-1259, 2009. 2. Herzog, W., Muller, K., Huisken, J., Stainier, D. Y. R. Genetic evidence for a noncanonical function of seryl-tRNA synthetase in vascular development. Circ. Res. 104: 1260-1266, 2009. Note: Erratum: Circ. Res. 105: e54 only, 2009. 3. Lo, W.-S., Gardiner, E., Xu, Z., Lau, C.-F., Wang, F., Zhou, J. J., Mendlein, J. D., Nangle, L. A., Chiang, K. P., Yang, X.-L., Au, K.-F., Wong, W. H., Guo, M., Zhang, M., Schimmel, P. Human tRNA synthetase catalytic nulls with diverse functions. Science 345: 328-332, 2014.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details

Target: Seryl-tRNA Synthetase (SARS)

Alternative Name: SARS1

Background:

Synonyms: Transcription factor GATA-4,GATA-binding factor 4,GATA4,

Tissue Specificity: Widely expressed in hematopoietic cells. Expressed in neutrophils. Within the B-cell compartment, expressed from pro- and pre-B cells to plasma cells.

Background: This gene belongs to the class II amino-acyl tRNA family. The encoded enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts. Multiple alternatively spliced transcript variants have been described but the biological validity of all variants is unknown.

Molecular Weight: 59 kDa

Gene ID: 6301

UniProt: P49591