REPS2 antibody (AA 76-564)

Catalog No. ABIN7602431

Product Details anti-REPS2 Antibody

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Binding Specificity: AA 76-564

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REPS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-REPS2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-REPS2 Antibody Picoband® (ABIN7602431). Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human REPS2 recombinant protein (Position: A76-K564). Human REPS2 shares 88.4% amino acid (aa) sequence identity with mouse REPS2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
1. Feig, L. A. Ral-GTPases: approaching their 15 minutes of fame. Trends. Cell Biol. 13: 419-425, 2003. 2. Ikeda, M., Ishida, O., Hinoi, T., Kishida, S., Kikuchi, A. Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. J. Biol. Chem. 273: 814-821, 1998. 3. Kariya, K., Koyama, S., Nakashima, S., Oshiro, T., Morinaka, K., Kikuchi, A. Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation. J. Biol. Chem. 275: 18399-18406, 2000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Alternative Name: REPS2 (REPS2 Products)

Background:

Synonyms: REPS2, POB1, RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2

Background: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 72 kDa

Gene ID: 9185

Pathways: EGFR Signaling Pathway