REPS2 antibody (N-Term)

Catalog No. ABIN657055

Product Details anti-REPS2 Antibody

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Binding Specificity: AA 153-182, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REPS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This REPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the N-terminal region of human REPS2.

Clone: RB32411

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Alternative Name: REPS2 (REPS2 Products)

Synonyms: POB1 antibody, RALBP1 associated Eps domain containing 2 antibody, RALBP1 associated Eps domain containing protein 2 antibody, REPS2 antibody, Reps2 antibody

Background: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 71534

NCBI Accession: NP_001074444, NP_004717

UniProt: Q8NFH8

Pathways: EGFR Signaling Pathway