RIN1 antibody (AA 76-669)

Catalog No. ABIN7602432

This Rabbit Polyclonal antibody specifically detects RIN1 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for RIN1 antibody (AA 76-669) (ABIN7602432)

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RIN1 Antibody

Binding Specificity: AA 76-669

Purpose: Anti-RIN1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RIN1 Antibody Picoband® (ABIN7602432). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RIN1 recombinant protein (Position: A76-N669).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Colicelli, J., Nicolette, C., Birchmeier, C., Rodgers, L., Riggs, M., Wigler, M. Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae. Proc. Nat. Acad. Sci. 88: 2913-2917, 1991. 2. Han, L., Colicelli, J. A human protein selected for interference with Ras function interacts ly with Ras and competes with Raf1. Molec. Cell. Biol. 15: 1318-1323, 1995. 3. Han, L., Wong, D., Dhaka, A., Afar, D., White, M., Xie, W., Herschman, H., Witte, O., Colicelli, J. Protein binding and signaling properties of RIN1 suggest a unique effector function. Proc. Nat. Acad. Sci. 94: 4954-4959, 1997.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RIN1

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Alternative Name: RIN1

Background:

Synonyms: Prolactin regulatory element-binding protein,Mammalian guanine nucleotide exchange factor mSec12,PREB,SEC12,

Tissue Specificity: Ubiquitous. .

Background: Ras and Rab interactor 1 is a protein that in humans is encoded by the RIN1 gene. Predicted to enable small GTPase binding activity. Predicted to be involved in endocytosis, regulation of catalytic activity, and signal transduction. Predicted to act upstream of or within associative learning, memory, and negative regulation of synaptic plasticity. Located in cytoplasm and plasma membrane.

Molecular Weight: 90 kDa

Gene ID: 9610

UniProt: Q13671