RASGRP3 antibody (AA 8-607)

Catalog No. ABIN7602495

This Rabbit Polyclonal antibody specifically detects RASGRP3 in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for RASGRP3 antibody (AA 8-607) (ABIN7602495)

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASGRP3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-RASGRP3 Antibody

Binding Specificity: AA 8-607

Purpose: Anti-RASGRP3 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-RASGRP3 Antibody Picoband® (ABIN7602495). Tested in ELISA, IHC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RASGRP3 recombinant protein (Position: K8-R607).

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry, 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Nagase, T., Ishikawa, K., Suyama, M., Kikuno, R., Hirosawa, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Oharo, O. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 5: 355-364, 1998. 2. Rebhun, J. F., Castro, A. F., Quilliam, L. A. Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase: regulation of MR-GEF by M-Ras-GTP interaction. J. Biol. Chem. 275: 34901-34908, 2000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RASGRP3

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Alternative Name: RASGRP3

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: Ras guanyl-releasing protein 3 is a protein that in humans is encoded by the RASGRP3 gene. The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers.

Molecular Weight: 100 kDa

Gene ID: 25780