TMC7 antibody (AA 8-723)

Catalog No. ABIN7602499

The Rabbit Polyclonal anti-TMC7 antibody has been validated for WB, ELISA, FACS, IF and IHC. It is suitable to detect TMC7 in samples from Human, Mouse and Rat.

Quick Overview for TMC7 antibody (AA 8-723) (ABIN7602499)

Target: TMC7 (Transmembrane Channel-Like 7 (TMC7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMC7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-TMC7 Antibody

Binding Specificity: AA 8-723

Purpose: Anti-TMC7 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TMC7 Antibody Picoband® (ABIN7602499). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TMC7 recombinant protein (Position: A8-N723).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Keresztes, G., Mutai, H., Heller, S. The TMC and EVER genes belong to a larger protein family, the TMC gene family encoding transmembrane proteins. BMC Genomics 4: 24, 2003. Note: Electronic Article. 2. Kurima, K., Yang, Y., Sorber, K., Griffith, A. J. Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis. Genomics 82: 300-308, 2003.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TMC7

Target: TMC7 (Transmembrane Channel-Like 7 (TMC7))

Alternative Name: TMC7

Background:

Synonyms: Interactor of HORMAD1 protein 1, Cancer/testis antigen 74, CT74, Coiled-coil domain-containing protein 36, CCDC36, IHO1

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in ion transmembrane transport. Predicted to be integral component of plasma membrane.

Molecular Weight: 90 kDa

Gene ID: 79905

UniProt: Q7Z402