Sorting Nexin 1 antibody (AA 83-505)

Catalog No. ABIN7602548

This anti-Sorting Nexin 1 antibody is a Rabbit Polyclonal antibody detecting Sorting Nexin 1 in WB, ELISA, IHC, IF, ICC and FACS. Suitable for Human.

Quick Overview for Sorting Nexin 1 antibody (AA 83-505) (ABIN7602548)

Target: Sorting Nexin 1 (SNX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorting Nexin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-Sorting Nexin 1 Antibody

Binding Specificity: AA 83-505

Purpose: Anti-SNX1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SNX1 Antibody Picoband® (ABIN7602548). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SNX1 recombinant protein (Position: Q83-Q505).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, D., Xiao, H., Zhang, K., Wang, B., Gao, Z., Jian, Y., Qi, X., Sun, J., Miao, L., Yang, C. Retromer is required for apoptotic cell clearance by phagocytic receptor recycling. Science 327: 1261-1264, 2010. 2. Haft, C. R., de la Luz Sierra, M., Barr, V. A., Haft, D. H., Taylor, S. I. Identification of a family of sorting nexin molecules and characterization of their association with receptors. Molec. Cell. Biol. 18: 7278-7287, 1998. 3. Kurten, R. C., Cadena, D. L., Gill, G. N. Enhanced degradation of EGF receptors by a sorting nexin, SNX1. Science 272: 1008-1010, 1996.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Sorting Nexin 1

Target: Sorting Nexin 1 (SNX1)

Alternative Name: SNX1

Background:

Synonyms: Neuronal PAS domain-containing protein 2,Neuronal PAS2,Basic-helix-loop-helix-PAS protein MOP4,Class E basic helix-loop-helix protein 9,bHLHe9,Member of PAS protein 4,PAS domain-containing protein 4,NPAS2,BHLHE9, MOP4, PASD4,

Background: Sorting nexin-1 is a protein that in humans is encoded by the SNX1 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.

Molecular Weight: 70-75 kDa

Gene ID: 6642

UniProt: Q13596