IAH1 antibody (AA 89-362)

Catalog No. ABIN7602606

This Rabbit Polyclonal antibody specifically detects IAH1 in WB, ELISA, FACS, ICC, IF and IHC. It exhibits reactivity toward Mouse, Human and Rat.

Quick Overview for IAH1 antibody (AA 89-362) (ABIN7602606)

Target: IAH1 (Isoamyl Acetate-Hydrolyzing Esterase 1 Homolog (IAH1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IAH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-IAH1 Antibody

Binding Specificity: AA 89-362

Purpose: Anti-IAH1 Antibody Picoband®

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-IAH1 Antibody Picoband® (ABIN7602606). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PARD6B recombinant protein (Position: L89-L362). Human PARD6B shares 89.1% amino acid (aa) sequence identity with mouse PARD6B.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kobayashi, M., Suzuki, M., Ohno, T., Tsuzuki, K., Taguchi, C., Tateishi, S., ... & Horio, F. (2016). Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12. BMC genetics, 17, 1-10. 2. Seppälä, I., Kleber, M. E., Lyytikäinen, L. P., Hernesniemi, J. A., Mäkelä, K. M., Oksala, N., ... & AtheroRemo Consortium. (2014). Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. European heart journal, 35(8), 524-531. 3. Am Seo, B., Kim, D., Hwang, H., Kim, M. S., Ma, S. X., Kwon, S. H., ... & Ko, H. S. (2021). TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease. Neuron, 109(23), 3758-3774.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for IAH1

Target: IAH1 (Isoamyl Acetate-Hydrolyzing Esterase 1 Homolog (IAH1))

Alternative Name: IAH1

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: IAH1, also referred to as Isoamyl acetate-hydrolyzing esterase 1 homolog, has 248 amino acids and is approximately 27 kDa. IAH1 is a member of the GDSL lipolytic enzyme family, and likely functions as a lipase. Research surrounding IAH1 has shown a possible link to alcoholism. IAH1 has also been shown to interact with alcohol dehydrogenase 5, ATP5O, CABC1, COQ2, and FAAH.

Molecular Weight: 28 kDa

Gene ID: 285148