CA1 antibody (AA 9-261)

Catalog No. ABIN7602620

This anti-CA1 antibody is a Mouse Monoclonal antibody detecting CA1 in WB and IHC. Suitable for Human, Rat and Mouse.

Quick Overview for CA1 antibody (AA 9-261) (ABIN7602620)

Target: CA1 (Carbonic Anhydrase I (CA1))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 2B5

Product Details anti-CA1 Antibody

Binding Specificity: AA 9-261

Purpose: Anti-Carbonic Anhydrase I/CA1 Picoband® Antibody (monoclonal, 2B5)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Carbonic Anhydrase I/CA1 Picoband® Antibody (monoclonal, 2B5) (ABIN7602620). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CA1 recombinant protein (Position: D9-F261). Human CA1 shares 78.5% and 81% amino acid (aa) sequence identity with mouse and rat CA1, respectively.

Isotype: IgG1

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
1. Lowe N, Edwards YH, Edwards M, Butterworth PH (Nov 1991). "Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8". Genomics 10 (4): 882-8. 2. "Entrez Gene: CA1 carbonic anhydrase I".

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CA1

Target: CA1 (Carbonic Anhydrase I (CA1))

Alternative Name: CA1

Background:

Synonyms: Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1, GLUT1

Tissue Specificity: Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.

Background: Carbonic anhydrase 1 is an enzyme that in humans is encoded by the CA1 gene. It is a member of the Carbonic anhydrase. The CA1 gene is mapped to 8q22. CAI has got about 260 amino acids. This protein is highly expressed in erythrocytes. As catalysts of the reversible hydration of carbon dioxide, CAI participates in a variety of biologic processes like respiration, calcification, acid-base balance etc.

Molecular Weight: 29 kDa

Gene ID: 759

UniProt: P00915