SERAC1 antibody (AA 97-623)
Quick Overview for SERAC1 antibody (AA 97-623) (ABIN7602709)
Target
See all SERAC1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 97-623
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Purpose
- Anti-SERAC1 Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-SERAC1 Antibody (ABIN7602709). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human SERAC1 recombinant protein (Position: E97-H623).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SERAC1 (Serine Active Site Containing 1 (SERAC1))
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Alternative Name
- SERAC1
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Background
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Synonyms: FERM domain-containing protein 6, Willin, FRMD6, C14orf31
Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
Background: Serine active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene. The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded protein plays a major role in mitochondrial function and intracellular cholesterol trafficking. Defects in this gene are a cause of 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
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Molecular Weight
- 74, 20 kDa
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Gene ID
- 84947
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Pathways
- Inositol Metabolic Process
Target
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