Centriolin antibody (AA 991-2187)

Catalog No. ABIN7602726

Product Details anti-Centriolin Antibody

Target: Centriolin (CNTRL)

Binding Specificity: AA 991-2187

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Centriolin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: Anti-CEP110/CNTRL Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-C-CNTRL Antibody Picoband® (ABIN7602726). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CEP110/CNTRL recombinant protein (Position: T991-E2187).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Guasch, G., Mack, G. J., Popovici, C., Dastugue, N., Birnbaum, D., Rattner, J. B., Pebusque, M.-J. FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8,9)(p12,q33). Blood 95: 1788-1796, 2000. 2. Ou, Y. Y., Mack, G. J., Zhang, M., Rattner, J. B. CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation. J. Cell Sci. 115: 1825-1835, 2002. 3. Popovici, C., Mattei, M.-G., Rattner, J. B., Birnbaum, D., Pebusque, M.-J. Assignment of the centrosomal protein 110 gene (Cep110) to mouse chromosome bands 2B-C1 by in situ hybridization. Cytogenet. Cell Genet. 89: 216-217, 2000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Centriolin

Target: Centriolin (CNTRL)

Alternative Name: CNTRL (CNTRL Products)

Background:

Synonyms: CNTRL, CEP1, CEP110, Centriolin, Centrosomal protein 1, Centrosomal protein of 110 kDa, Cep110

Background: Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110. This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1.

Molecular Weight: 269 kDa

Gene ID: 11064

UniProt: Q7Z7A1

Pathways: M Phase, SARS-CoV-2 Protein Interactome