HIST1H2AB antibody (acLys9)

Catalog No. ABIN7602735

This Rabbit Monoclonal antibody specifically detects HIST1H2AB in WB, IHC, ICC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HIST1H2AB antibody (acLys9) (ABIN7602735)

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HIST1H2AB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: DEB-8

Product Details anti-HIST1H2AB Antibody

Binding Specificity: acLys9

Purpose: Anti-Histone H2A (acetyl K9) HIST1H2AB Monoclonal Antibody

Characteristics: Anti-Histone H2A (acetyl K9) HIST1H2AB Monoclonal Antibody (ABIN7602735). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Histone H2A (acetyl K9) Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:500-1:1000
ICC/IF 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for HIST1H2AB

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Alternative Name: HIST1H2AB

Background:

Synonyms: Histone H2A type 1-B/E,Histone H2A.2,Histone H2A/a,Histone H2A/m,HIST1H2AB,H2AFM,HIST1H2AE,H2AFA,

Tissue Specificity: Widely expressed with highest levels in brain, kidney and muscle. .

Molecular Weight: 37 kDa

UniProt: P04908

Pathways: Telomere Maintenance