NAT8L antibody (C-Term)

Catalog No. ABIN7602765

This Rabbit Polyclonal antibody specifically detects NAT8L in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for NAT8L antibody (C-Term) (ABIN7602765)

Target: NAT8L (N-Acetyltransferase 8-Like (GCN5-Related, Putative) (NAT8L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAT8L antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-NAT8L Antibody

Binding Specificity: C-Term

Purpose: Anti-NAT8L Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-NAT8L Antibody Picoband® (ABIN7602765). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human NAT8L, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: "Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
"1. Evans DA (1989). "N-acetyltransferase". Pharmacology & Therapeutics. 42 (2): 157-234. 2. Ma Y, Ghoshdastider U, Wang J, Ye W, Dötsch V, Filipek S, Bernhard F, Wang X (2012). "Cell-free expression of human glucosamine 6-phosphate N-acetyltransferase (HsGNA1) for inhibitor screening". Protein Expr. Purif. 86 (2): 120-6. 3. Sim, Edith, Lack, Nathan, Wang, Chan-Ju, et al. (May 2008). "Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms". Toxicology. 254 (3): 170-183.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for NAT8L

Target: NAT8L (N-Acetyltransferase 8-Like (GCN5-Related, Putative) (NAT8L))

Alternative Name: NAT8L

Background:

Synonyms: N-acetylaspartate synthetase, NAA synthetase, Camello-like protein 3, N-acetyltransferase 8-like protein, NAT8L, CML3

Tissue Specificity: Expressed in brain.

Background: N-acetyltransferase (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, arylhydroxylamines and arylhydrazines. It is mapped to 4p16.3. This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia).

Molecular Weight: 33 kDa

Gene ID: 339983

UniProt: Q8N9F0